Monica Dettin

Centre for Mechanics of Biological Materials - University of Padova
tel +39 049 8275553 - fax +39 049 8275555 - e-mail monica.dettin[at]


Date of birth: December, 13, 1964

Monica Dettin is Assistant Professor of Organic Chemistry at the Department of Industrial Engineering, University of Padova. Research interests are focused on the following areas: synthesis and characterization of biologically active biopolymers; studies on structure-activity relationship in biopolymers; conformational and structural studies; maturation process of pro-proteins; interaction between biomaterials and biological tissues; peptide mimicry of adhesive proteins and growth factors; scaffolds of self-assembling peptides; chemoselective ligation.

Educational activity
Teaching activity is carried out in the area of organic chemistry and chemistry of biological molecules.

Membership and Appointment
Member of the American Chemical Society and European Peptide Society.



[max 10 publications
in the last 3 years]

Gazza F, D'Arrigo D, Graiani G, Zamuner A, Zedda M, Manfredi E, Dettin M, Cacchioli A. "Enhancement of peri-implant bone osteogenic activity induced by a peptidomimetic functionalization of titanium". Annals of Anatomy, 218, 165-174, (2018)

Forte G, Messina GML, Zamuner A, Dettin M, Grassi A, Marletta G. "Surface-driven first-step events of nanoscale self-assembly for molecular peptide fibers:An experimental and theoretical study". Colloids and Surfaces B: Biointerfaces, 168, 148-155, (2018)

Rampazzo E, Dettin M, Maule F, Scabello F, Calvanese L, D'Auria G, Falcigno L, Porc¨ E, Zamuner A, Della Puppa A, Boso D, Basso G, Persano L. "A synthetic BMP-2 peptide induces glioblastoma stem cell differentiation". BBA - General Subjects 1861, 2282-2292, (2017).

Zamuner A, Brun P, Scorzeto M, Sica G, Castagliuolo I, Dettin M. "Smart biomaterials: Surfaces functionalized with proteolytically stable osteoblast-adhesive peptides".Bioactive Materials 2, 121-130, (2017).

Dettin M, Zamuner A, Naso F, Monteleone A, Spina M, Gerosa G. "Natural Scaffolds for Regenerative Medicine: Direct Determination of Detergents Entrapped in Decellularized Heart Valves". BioMed Research International, 2017, ID 9274135 9 (2017).

Facchin S, Digiglio L, D'IncÓ R, Casarin E, Dassie E, Dettin M, Zamuner A, Buda A, De Boni M, Libera DD, D'Urso A, Sturniolo GC, Morpurgo M. "Discrimination between ulcerative colitis and Crohn's disease using phage display identified peptides and virus-mimicking synthetic nanoparticles.". Nanomedicine, 13, 2027-2036, (2017).

Zamuner, M. Cavo, S. Scaglione, G.M.L. Messina, T. Russo, A. Gloria, G. Marletta, M. Dettin "Design of Decorated Self-Assembling Peptide Hydrogels as Architecture for Mesenchymal Stem Cells". Materials, 9, 727, (2016).

Dettin M., Zamuner A., Roso M., Gloria A., Iucci G., Messina G.M.L., Marletta G., Modesti M., Castagliuolo I., Brun P. "Electrospun scaffolds for regenerative medicine: peptide-induced concentration-dependent improvements of poly-?-caprolactone". PLOS ONE, DOI:10.1371/journal.pone.0137505 (2015).

Dettin M., Zamuner A., Roso M., Iucci G., Samouillan V., Danesin R., Modesti M., Conconi M.T. "Facile and selective covalent grafting of a RGD-peptide to electrospun scaffolds improves HUVEC adhesion". J Pept Sci, 21, 786-795 (2015).

Silvestri D, Sonato A, Ruffato G, Meneghello A, Antognoli A, Cretaio E, Dettin M, Zamuner A, Casarin E, Zacco G, Romanato F, Morpurgo M. "A peptide nucleic acid label-free biosensor for Mycobacterium Tuberculosis DNA detection via azimuthally-controlled grating-coupling SPR". Analytical Methods, 7, 4173-4180 (2015)




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