Carlo Reggiani
Centre for Mechanics of Biological Materials - University of Padova
tel +39 049 8275313 - fax +39 049 8275604 - e-mail carlo.reggiani[at]unipd.it
Date of birth:
Carlo Reggiani is full Professor of Physiology, University of Padova. He received the Medical degree at the University of Pavia (1972). Developed his research training contract at the University of Pavia (1974-78). He was Visiting scientist at the Dept of Pharmacology, University of Lund (Sweden), laboratory of K.A. Edman (1980-84). He is author of 156 original articles with 4860 citations, h index 32 (Scopus). He is editor of Journal of Physiology, Member of the Editorial Board of American Journal Physiology-Cell Physiology, Associate Editor of BMC Physiol. Active Reviewer for: J. Physiol, American Journal Physiology, Pflugers Arch (Europ. J. Physiol.), J. Appl. Physiol., FEBS. J.
Educational activity
Teaching activity is developed in Physiology at the Medical School of the University of Padova (1999 to present). He was the supervisor of 20 PhD students in Italy and co-supervisor of 4 PhD students in other European countries (France, Netherland, Sweden).
Main Research Topics
He is PI of the laboratory of Muscle Biophysics at the Dept. of Biomedical Sciences, University of Padova since 1999, and themain research lines are: structure-function relation of myosin and myosin isoforms, myosin isoform expression, intracellular signals and gene expression regulation.
Membership and Appointment
1) European Union: (1995-98, FP4 ) grant “ Energy transduction in muscle “, (1999-02, FP5) grant “Energy transduction in muscle and related motility systems: structure, function and mechanics“, (2009-2012 FP7) grant MYOAGE ,
2) PRIN grants (MIUR): 1998-00: “Mechano-chemical transduction in sarcomeric myosins”, 2000-02: “Mechano-chemical transduction in sarcomeric myosins :Structure-function relation in myosin orthologous isoforms, 2002-04: “Mechano-chemical transduction in sarcomeric myosins :From gene to protein and function”, 2004-06: “Mechano-chemical transduction in sarcomeric myosins : Sarcomeric Myosin Isoforms”, 2006-08 “Regulatory mechanisms in muscle plasticity”,
3) Telethon grants: n 373 (1994-97): “ Hyperthyroid and hypothyroid myopathies”, n 1017 (1998-99): “A novel mechanism of calcium mediated regulation of muscle contraction”, n GP0229Y01 (2001-03) ”The dystrophin mediated link between cytoskeleton and extracellular matrix“, n GGP04113 (2004-05) “Collagen VI myopathies: from mouse therapy to human trials”, n GGP 08153 (2009-2012) “Calsequestrins in calcium homeostasis and potential role in inherited human skeletal muscle diseases.”,
4) Italian Space Agency (ASI) grants 1997-99, 1999-02, 2006-09.
Publications
[max
10 publications
in the last 3 years]
Canato M, Capitanio P, Reggiani C, Cancellara L. The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models? J Muscle Res Cell Motil. 2014 Nov 26. [Epub ahead of print] PubMed PMID: 25424378. IF 1.934
C. Reggiani, Who can better resist the adverse effects of disuse on muscles: men or women?, The Journal of Physiology, 2014 Oct, 592(20):4415-6, doi: 10.1113/jphysiol.2014.280933, PubMed PMID: 25320156, IF 4.544.
D. Rossi, B. Vezzani, L. Galli, C. Paolini, L. Toniolo, E. Pierantozzi, S. Spinozzi, V. Barone, E. Pegoraro, L. Bello, G. Cenacchi, G. Vattemi, G. Tomelleri, G. Ricci, G. Siciliano, F. Protasi, C. Reggiani, V.Sorrentino, A Mutation in the CASQ1 Gene Causes a Vacuolar Myopathy with Accumulation of Sarcoplasmic Reticulum Protein Aggregates, Human Mutation, 2014 Oct, 35(10):1163-70, doi: 10.1002/humu.22631, PubMed PMID: 25116801, PubMed Central PMCID: PMC4177304, IF 5.05.
M. Venturelli, G.R. Morgan, A.J. Donato, V. Reese, R. Bottura, C. Tarperi, C. Milanese, F. Schena, C. Reggiani, F. Naro, R.M. Cawthon, R.S. Richardson, Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age, Clinical Science, 2014 Sep, 127(6):415-21, doi: 10.1042/CS20140051, PubMed PMID: 24708050, IF 5.629.
E. Trevellin, M. Scorzeto, M. Olivieri, M. Granzotto, A. Valerio, L. Tedesco, R. Fabris, R. Serra, M. Quarta, C. Reggiani, E. Nisoli, R. Vettor, Exercise training induces mitochondrial biogenesis and glucose uptake in subcutaneous adipose tissue through eNOS-dependent mechanisms, Diabetes, 2014 Aug, 63(8):2800-11, doi: 10.2337/db13-1234, PubMed PMID: 24622799, IF 8.474.
C. Reggiani, Calcium handling in muscle fibres of mice and men: evolutionary adaptation in different species to optimize performance and save energy, The Journal of Physiology, 2014 Mar, 592(6):1173-4, doi: 10.1113/jphysiol.2014.272344, PubMed PMID: 24634016, PubMed Central PMCID: PMC3961076, IF 4.544.
B. Blaauw, C. Reggiani, The role of satellite cells in muscle hypertrophy, Journal of Muscle Research and Cell Motility, 2014, 35(1):3-10, doi: 10.1007/s10974-014-9376-y, IF 1.934.
M. Scorzeto, M. Giacomello, L. Toniolo, M. Canato, B. Blaauw, C. Paolini, F. Protasi, C. Reggiani, G.J. Stienen. Mitochondrial Ca(2+)-Handling in Fast Skeletal Muscle Fibers from Wild Type and Calsequestrin-Null Mice, PLoS One, 2013 Oct, 8(10):e74919, PubMed PMID: 24098358, PubMed Central PMCID: PMC3789688.
B. Blaauw, S. Schiaffino, C. Reggiani, Mechanisms modulating skeletal muscle phenotype, Comprehensive Physiology, 2013 Oct, 3(4):1645-87, doi: 10.1002/cphy.c130009, PubMed PMID: 24265241.
M. Tomasi, M. Canato, C. Paolini, M. Dainese, C. Reggiani, P. Volpe, F. Protasi, A. Nori, Calsequestrin (CASQ1) rescues function and structure of calcium release units in skeletal muscles of CASQ1-null mice, American Journal of Physiology, 2012 Feb, 302(3):C575-86, PubMed PMID: 22049211.
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