Emanuele Luigi Carniel
Department of Industrial Engineering, University of Padova
Via Venezia 1, 35131 Padova, Italy
tel +39 049 8276876
e-mail emanueleluigi.carniel@unipd.it

Research Activity

As part of the multidisciplinary Centre for Mechanics of Biological Materials, Emanuele Luigi Carniel and his group conduct research on the mechanical functionality of biological tissues and structures. Researchers from a variety of disciplines, including engineering, materials science, computer science, mathematics, anatomy, physiology, medicine, and surgery, collaborate on these projects.
The goal of the research activities is to optimize biomedical devices and surgical techniques, with a focus on mechanical and mechano-biological factors. Activities are defined with consideration for the real demand in clinical and surgical practice as well as collaboration with biomedical industry partners.
The investigation’s key topics are lower urinary tract mechanical functionality, as well as gastrointestinal structures mechano-physiology and joints mechanics. Using a revolutionary research methodology, novel techniques and devices are logically designed and validated through the synergistic integration of in vitro experiments on human and animal tissues and structures, in vivo experimentations on animal models, and in silico mathematical modeling. Experiments are designed to precisely characterize and identify computer models of the anatomical districts. These models are then utilized to assess the functional response under a variety of conditions. The chosen method maximizes reproducibility while decreasing the need for biological samples.

Five most representative publications

• Mascolini, M.V., Fontanella, C.G., Berardo, A., Carniel, E.L., Influence of transurethral catheters on urine pressure-flow relationships in males: A computational fluid-dynamics study
  (2023) Computer Methods and Programs in Biomedicine, 238, art. no. 107594.
  DOI: 10.1016/j.cmpb.2023.107594
• Toniolo, I., Berardo, A., Gagner, M., Foletto, M., Carniel, E.L., Unveiling the effects of key factors in enhancing gastroesophageal reflux: A fluid-structure analysis before and after laparoscopic sleeve gastrectomy (2023) Computer Methods and Programs in Biomedicine, 231, art. no. 107409.
  DOI: 10.1016/j.cmpb.2023.107409
• Fontanella, C.G., Belluzzi, E., Pozzuoli, A., Favero, M., Ruggieri, P., Macchi, V., Carniel, E.L., Mechanical behavior of infrapatellar fat pad of patients affected by osteoarthritis (2022) Journal of Biomechanics, 131, art. no. 110931.
  DOI: 10.1016/j.jbiomech.2021.110931
• Toniolo, I., Fontanella, C.G., Foletto, M., Carniel, E.L., Coupled experimental and computational approach to stomach biomechanics: Towards a validated characterization of gastric tissues mechanical properties (2022) Journal of the Mechanical Behavior of Biomedical Materials, 125, art. no. 104914.
  DOI: 10.1016/j.jmbbm.2021.104914
• Carniel, E.L., Albanese, A., Fontanella, C.G., Pavan, P.G., Prevedello, L., Salmaso, C., Todros, S., Toniolo, I., Foletto, M., Biomechanics of stomach tissues and structure in patients with obesity (2020) Journal of the Mechanical Behavior of Biomedical Materials, 110, art. no. 103883.
  DOI: 10.1016/j.jmbbm.2020.103883