Research

The CMBM Group of Cardiovascular Sciences, directed by Prof. Gerosa, aims at developing increasingly efficient treatments for cardiovascular diseases, the main cause of mortality worldwide. The key research topics are heart failure to be treated with ventricular assistance devices and total artificial hearts. Furthermore, great importance is given to find new therapeutic solutions for valve insufficiency. In this regard, new valve repair techniques have been devised for mitral valve insufficiency and the most modern technologies for the treatment of aortic valve insufficiency are adopted, also in a minimally invasive way. The group is also involved in developing new bioengineered valve substitutes in the laboratory, starting from decellularized tissues, with superior performance and biocompatibility properties (Figure 1) compared to those shown by current commercialized biological and mechanical prostheses.